For all of human history, eating meat has meant slaughtering animals. But scientists behind cultivated meat say that's no longer necessary. They produce meat by growing cells extracted from an animal's body. And, today, the U.S. Department of Agriculture gave its first clearances to sell meat produced this way.

GOOD Meat, a division of Eat Just, Inc., announced that it has received approval from the USDA for its first poultry product, cultivated chicken, grown directly from animal cells, to be sold in the U.S.

"This announcement that we're now able to produce and sell cultivated meat in the United States is a major moment for our company, the industry and the food system, " said Josh Tetrick, co-founder and CEO of GOOD Meat and Eat Just.

GOOD Meat already sells its cultivated chicken in Singapore, which in 2020 became the first country to allow commercial sales of cultivated meat.

The USDA has also cleared the sale of UPSIDE Food's cultivated chicken. "This represents a historic step," Uma Valeti, CEO of UPSIDE Foods told NPR by text. The company also produces chicken grown directly from animal cells.

UPSIDE will debut with a textured chicken product, which tastes very similar to chicken breast and is made from over 99% chicken cells. I tasted it during a tour of the company's 70,000-square-foot production facility in Emeryville, Calif., where its meat is grown in large stainless steel tanks resembling a brewery.

I was served a piece of their chicken, pan-fried in a white-wine butter sauce. My first reaction: "It's delicious." (Isn't everything in wine-butter sauce?) And the texture was chewy, closely replicating the texture of chicken breast (minus bones, and tough bits or gristle.) "It tastes like chicken," I said, to which Valeti quickly replied, "It is chicken!"

At the outset, UPSIDE Food's facility can produce about 50,000 pounds of meat per year, with plans to expand beyond chicken, once this product is launched.

As NPR reported last fall, the U.S. Food and Drug Administration gave UPSIDE a greenlight, signaling its cultivated chicken is safe to eat. Last week, the U.S. Department of Agriculture approved UPSIDE's label, and today (Wednesday) the USDA issued a grant of inspection, which means the company has cleared the final regulatory hurdle and can begin sales.

"Today's historic announcement — two American companies earning regulatory approval to bring cultivated meat to U.S. consumers — marks a pivotal moment in food and agriculture," says Bruce Friedrich, president of the Good Food Institute, a non-profit that tracks investment trends in alternative proteins.

"Consumers are now one giant step closer to enjoying the meat they love without compromise," Friedrich says, pointing out that the goal is to give people the taste of meat without slaughtering animals and without the environmental footprint linked to traditional animal food production. More than 150 companies dedicated to producing cultivated meat and seafood have raised more than $2.8 billion dollars in investments.

"Everything we know about how meat can be made is going to change," Valeti says, who is a cardiologist, by training. "This is real," he told us. But don't expect to see cultivated meat in grocery stores just yet. UPSIDE's strategy is to build awareness about cultivated meat, promoting it as a way to build a more humane and sustainable food system. And the company knows its future depends on selling taste, too, which explains the partnership with a Michelin-starred chef.

Dominique Crenn, owner of the three-Michelin-starred restaurant Atelier Crenn, will serve UPSIDE's cultivated chicken at her restaurant Bar Crenn in San Francisco. And GOOD Meat has partnered with celebrity chef Jose Andres, who joined GOOD Meat's board of directors. Andres plans to serve GOOD Meat's cultivated chicken in one of his restaurants.

"We need to innovate, to adapt our food to a planet in crisis," Andres said when he partnered with GOOD Meat. The company markets its cultivated meat as "real" meat made "without tearing down a forest or taking a life."

Proponents say the cultivated meat is more sustainable and can be produced without antibiotics, and without producing methane emissions linked to animal agriculture, particularly beef cattle. And scientists warn that the typical way meat is produced now, in concentrated animal feeding operations, is a risk factor for the emergence of diseases.

About one third of human-induced greenhouse gas emissions come from producing food, and animal agriculture is responsible for much of it. Climate scientists have warned that to slow global warming, agriculture must change. Some scientists say it's uncertain whether cultivated meat can reduce greenhouse gas emissions – it will depend, in part, on the source of the electricity used to power its facilities.

Though many of the details are proprietary, the basic formula to produce cultivated meat is clear. It begins by extracting cells from animals using a needle biopsy. Food scientists no longer need to go back to the animal to extract cells every time, since there are lots of cells stored in a cell bank. The companies can select the cells they want to grow. Then, inside the stainless steel tanks, the cells are fed a mix of the same nutrients an animal would eat, a combination of fats, sugar, amino acids and vitamins, which allows the cells to proliferate and grow into meat.

UPSIDE says people who want to try their meat can check out their Instagram and Twitter accounts for a chance to join in on the first meal with Chef Crenn.

Copyright 2023 NPR. To see more, visit https://www.npr.org.

Transcript

JUANA SUMMERS, HOST:

The U.S. Department of Agriculture has, for the first time in history, given a green light to two U.S. companies to sell meat that is grown directly from animal cells without slaughtering the animal. Until recently, it was called lab-grown meat, since scientists were developing it in labs. Now, though, the labs have been replaced by production facilities that can grow tens of thousands of pounds of meat a year.

NPR's Allison Aubrey has visited these companies and tasted the meat and joins us now. Hey, Allison.

ALLISON AUBREY, BYLINE: Hi there.

SUMMERS: So Allison, what exactly did the USDA approve today?

AUBREY: Well, for thousands of years, eating meat has meant slaughtering animals. But the scientists behind the two companies that received USDA clearance today say that's no longer necessary. Instead, they produce meat by extracting cells from an animal's body, and then they feed the cells and literally grow meat in big stainless steel tanks. Their production facilities look like breweries almost, but instead of beer, they're brewing meat, so to speak.

SUMMERS: I do not know how I feel about that.

AUBREY: (Laughter).

SUMMERS: But, OK, let's go on here. We have been hearing about so-called fake meat for a long time now. I mean, a lot of us have eaten our fair share of veggie burgers or Impossible burgers over the years, but what makes this different?

AUBREY: This is nothing like the Impossible burger or a veggie burger, which are made from vegetable proteins - so soy, potato protein and a bunch of other ingredients that are mixed together to taste like meat. What's approved for sale today actually is meat. When I visited Upside Foods, which is headquartered in Berkeley, they prepared their chicken, which is grown directly from chicken cells - it's more than 99% chicken cells. It was pan-seared in a kind of lovely, buttery wine sauce.

SUMMERS: I mean, Allison, you're kind of burying the lead here. How did it taste? How was it?

AUBREY: You know, I think almost anything cooked in butter and wine probably tastes good, right?

SUMMERS: Oh, yeah.

AUBREY: What did impress me is the texture. They've basically replicated the texture of chicken breast. I told the CEO of Upside Foods, Uma Valeti, hey, it tastes just like chicken.

UMA VALETI: It is chicken. It is just chicken grown directly from animal cells in a different way, in a very clean, controlled environment.

AUBREY: Now, Dr. Valeti is a cardiologist who became a vegetarian, but he loves the taste of meat. And he thinks this is a better way to produce meat, one that could be better for the environment. And as the son of a veterinarian, he likes the idea of sparing animals' lives.

SUMMERS: OK, so where can people buy it or get a taste of it?

AUBREY: Right now, don't expect to see it in grocery stores. To start out, both companies have kind of teamed up with famous chefs. Upside Foods is working with chef Dominique Crenn, a Michelin-starred chef in San Francisco. And Good Meat, the other company that got clearance today, has partnered with megastar Jose Andres, who will serve cultivated chicken at one of his restaurants.

SUMMERS: I mean, so why should people want this? What is wrong with the way that meat's produced today?

AUBREY: It depends on who you ask. The traditional meat industry says the status quo is efficient, but meat production has a big environmental footprint. I talked to Bruce Friedrich, who heads the nonprofit Good Food Institute. He tracks investments in protein alternatives and says there are more than 150 companies working to bring cultivated meat and seafood to market. Some are working on beef. He says global demand for meat is expected to double by 2050.

BRUCE FRIEDRICH: Cultivated meat gives consumers everything that they like about meat, but it requires a fraction of the land, requires significantly less water.

AUBREY: Now, it remains to be seen whether cultivated meat production can lower greenhouse gas emissions from producing meat. But what is clear is that now that cultivated meat is approved for sale, it is no longer science fiction. People will get a chance to taste it.

SUMMERS: All right. That is NPR's Allison Aubrey. Thank you so much.

AUBREY: Thank you. Great to be here.

(SOUNDBITE OF LIL WAYNE SONG, "SHOOTER") Transcript provided by NPR, Copyright NPR.

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