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Robert Siegel talks to Deborah Amos about heavy fighting that has broken out in the Syrian capital of Damascus. Government troops — reportedly backed by helicopter gunships — are battling rebels in at least four districts of the capital. Some Syrian activists say the 16 month uprising is reaching a tipping point.

It's difficult to build a working four-rotor helicopter that spans 100 feet and only weighs 80 pounds. It's even harder when your engine is a 0.7-horsepower person. But two teams of young engineers hope to do just that.

Fifty years ago, a United States Air Force U-2 spyplane captured photographic proof that the Soviet Union was installing offensive nuclear missile sites in Cuba, and a diplomatic standoff ensued. Weekend Edition host Rachel Martin talks with Graham Allison, director of the Belfer Center for Science and International Affairs and professor at Harvard's John F. Kennedy School of Government about the lessons learned from the Cuban Missile Crisis.

Following the FDA approval of Truvada — the once-a-day pill that can drastically lower a person's risk of contracting HIV — Audie Cornish talks with Dr. Wafaa El-Sadr of Columbia University's Mailman School of Public Health. They examine the status of HIV prevention efforts in the U.S. today — what progress has been made and the challenges that still ahead. El-Sadr has worked on HIV/AIDS prevention and treatment since 1981.

The vegan burger weighed 358 pounds, 4 ounces and spent nine hours cooking. The company, Finnebrogue Artisan, earned a Guinness World Record.

The Justice Department's internal watchdog determined the FBI had sufficient evidence to open the Russia probe but criticized the bureau over its surveillance of a former Trump campaign adviser.

Electronic composer Jlin warps percussion and other-worldly sounds into a fascinating, challenging collage. On a new album, she also gets a bit more... straightforward.

NPR's Noel King speaks to Gina McCarthy, White House National Climate Adviser, about President Biden's order to make federal vehicles and buildings carbon neutral by 2050.

House Democrats to unveil articles of impeachment against President Trump. Russia and Ukraine's presidents agree to a cease-fire. A lawsuit claims SAT and ACT are illegal in California admissions.

An investigation is underway into Wednesday's helicopter crash that killed India's top military leader — along with 12 other people, including his wife.