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Japan's Prime Minister Shigeru Ishiba has expressed his intention on Sunday to step down following growing calls from his party to take responsibility for a historic defeat in July's parliamentary election.

A special election in what should be a safe seat for Republicans has proven to be more competitive than expected as polls close Tuesday.

The Food and Drug Administration says it's going to get tougher on vaccines, blaming the deaths of at least 10 children on the COVID-19 vaccines.

The deadly attack on U.S. forces in Syria underscores the challenges facing the new Syrian president one year into his rule of the fractious nation.

As the conclave to select a new pope gets under way at the Vatican, what do American Catholics want from the next pontiff? Renee Montagne speaks with Greg Smith of the Pew Forum on Religion & Public Life about their most recent survey.

St. Louis is fighting to keep its NFL team from bolting to Los Angeles. Proponents see an economic benefit to keeping the team, and they fear losing of the Rams will hurt the city's prestige.

Nearly 500,000 people have petitioned the Securities and Exchange Commission to make publicly-traded corporations disclose their political spending. The question is: How much clout do 500,000 people actually have?

Renee Montagne talks with Ofeibea Quist-Arcton about South Africa's 10-day goodbye to Nelson Mandela. His body will lie in state at the Union Buildings in Pretoria, the scene of his presidential inauguration in 1994.

Attorney General Loretta Lynch traveled to Baltimore Tuesday to meet with the family of Freddie Gray, police, local officials and members of the community.

Around the world, many of us start our day with a drug derived from a natural insecticide: caffeine. Murray Carpenter tells the tale in Caffeinated: How Our Daily Habit Helps, Hurts and Hooks Us.