Science

Appalachian State receives enzyme research grant from NIH

By Paul Garber, Liam Kimbro

Published February 15, 2023 at 1:14 PM EST

The National Institutes of Health has awarded a nearly $1.6 million grant to Appalachian State University for research surrounding enzyme treatments for diseases including cancer.

University officials say it’s the largest NIH grant in Appalachian State’s history.

Assistant Professor Michael Reddish’s lab focuses on the study of P450 enzymes. They are involved in the body’s metabolism of steroid hormones, pharmaceuticals, carcinogens and fat-soluble vitamins.

Results of the study could help determine when drug levels need to be adjusted to make treatments associated with these enzymes more effective.

The grant runs through June 2027 and will join other funding awarded to Reddish’s lab in recent years for ongoing enzyme research.

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Paul Garber

Paul Garber is a Winston-Salem native and an award-winning reporter who began his journalism career with an internship at The High Point Enterprise in 1993. He has previously worked at The Augusta (Ga.) Chronicle, The St. Louis Post-Dispatch, The News and Record of Greensboro and the Winston-Salem Journal, where he was the newspaper's first full-time multimedia reporter. He won the statewide Media and the Law award in 2000 and has also been recognized for his business, investigative and multimedia reporting. Paul earned a BA from Wake Forest University and has a Master's of Liberal Arts degree from Johns Hopkins University and a Master's of Journalism and Mass Communication from the University of North Carolina at Chapel Hill. He lives in Lewisville.

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Appalachian State receives enzyme research grant from NIH

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