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Appalachian State receives enzyme research grant from NIH

Assistant Professor Michael Reddish works in Appalachian State University's Department of Chemistry and Fermentation Sciences. Photo by Chase Reynolds courtesy of Appalachian State.

Assistant Professor Michael Reddish works in Appalachian State University's Department of Chemistry and Fermentation Sciences. Photo by Chase Reynolds courtesy of Appalachian State.

The National Institutes of Health has awarded a nearly $1.6 million grant to Appalachian State University for research surrounding enzyme treatments for diseases including cancer.

University officials say it’s the largest NIH grant in Appalachian State’s history. 

Assistant Professor Michael Reddish’s lab focuses on the study of P450 enzymes. They are involved in the body’s metabolism of steroid hormones, pharmaceuticals, carcinogens and fat-soluble vitamins.

Results of the study could help determine when drug levels need to be adjusted to make treatments associated with these enzymes more effective. 

The grant runs through June 2027 and will join other funding awarded to Reddish’s lab in recent years for ongoing enzyme research. 

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